Peptide Modification Services

There are many contents of peptide labeling and peptide modification, commonly used are N-terminal labeling or modification, N-terminal fluorescein, photosensitizer, N-terminal fatty acid, C-terminal labeling or modification, phosphorylation, disulfide cyclization, lysine modification, high amino-acid modification, PEG modification, single and double labeling, azide modification, Mal modification, N-Me modification, coupling and so on. It is widely used in the research of polypeptide drugs, polypeptide biology, polypeptide antibodies and polypeptide reagents. At present, it is widely used in non-radionuclide labeling (C13, H2, N15), fluorescent labeling (FAM, FITC, etc.), biological labeling, phosphorylation modification, etc. The specific situation can be WeChat, email, Whatsapp consultation:

Detailed classification:
C-terminal labeling techniqueAmidation,C-termainal
Aldehydes
Alcohols
pNA (p-Nitroanilide)
AMC
AFC
Cysteamide
Ester
N-Alkyl Amides
 N-terminal labeling techniqueAcetylated
Palmytolyl
HYNIC
Biotinylated
Bromoacetylated
DOTA,DTPA conjugated
Formylated
Tetradecyl, octadecyl (Myristoylated)
Succinylation, palmitization, apple acidification, lipid acidification, etc.(N-Succinylated)
Fluorescent labeling modificationC-terminal modification: AFC,AMC,Dap(Dnp),Lys(Dye),pNA, Rh110
terminal modification: Bodipy-FL, Cy3, Cy5, Texas Red, 5-Tamra, 5-lodoacetamido fluorescein
Rhodamine 110 and Rhodamine B Luciferin, EDANS 
FAM, FITC, MCA, Rox, Sulforhodamine 101, 5-TAMRA
Cyclization reactionEnd to end ring, middle ring, special ring (N -> C or Head to Tail)
2 Disulfide,3 Disulfide (Disulfide(S-S bond formation).Trisulfide formation)
Natural product active peptides (Cyclic-natural peptides)
 Methylation modificationSide chain methylation Lys (For), Lys (Me), Lys (Me) 2, Lys (Me) 3, Arg (Me) 2 symmetrical, D-Tyr (Me), D-Tyr (Et)
N-terminal methylation(N-Me-Arg,N-Me-Asp,N-Me-Glu, N-Me-Leu,N-Me-Nle,N-Me-Nva,N-Me-Phe,N-Me-S N-Me-Ser, N-Me-Trp,N-Me-Thr,N-Me-Val)
Several special modificationsVarious coupling(BSA, KLH conjugated peptides for antibody production)
Phosphorylation(Phosphoserine,Phosphothreonine,Phosphotyrosine)
Sulfonation (Sulfated Tyrosine or Serine)
MAPS (Multiple Antigenic Peptide)
Glycopeptides
PEGylation

Greatpeptide company provides a variety of modifications, the following is part of the modification price list, for reference only, according to the difficulty of the sequence to give the corresponding discount, the specific situation can be whatsApp, email, WeChat consultation.

5 mg 10mg20 mg
N-terminal modifications   
N-Acetylation( Free )FreeFreeFree
N-Formylated FreeFreeFree
N-Myristoylated¥200¥300¥400
N-Succinylated¥200¥300¥400
N-Biotinlytion¥300¥500¥800
N-terminal Fatty acid¥200¥300¥500
N-Rhodamine B¥400¥500¥800
N-FITC, 5-FAM,6-FAM¥400¥600¥800
N-Bromoacetylated¥500¥800¥1000
N-Alkyl Amides ¥500¥800¥1000
DOTA, DTPA, Hynic conjugated¥800¥1200¥1600
N-BODIPY,Cy3,Cy5quotation requestquotation requestquotation request
C-terminal modifications   
C-AmidationFreeFreeFree
C-Aldehydes¥800¥1200¥1500
C-Alcohols¥800¥1200¥1500
C-Chloromethyl Ketones¥800¥1200¥1500
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