High quality Fmoc amino acids were synthesized by Fmoc solid phase synthesis process, and the polypeptide with amide bond was obtained. The product was purified by HPLC. The final product provides the corresponding mass spectrum, purity analysis of HPLC chromatogram, and COA.
A polypeptide that rings from the beginning to the end of the amide bond.
Cyclic peptides with amide bond side chains (Glu, Asp, Lys,Orn)
The Case of Amide Bond Ring Polypeptide Synthesis
a. Cyclo（RGDfK）: Cyclo（Arg-Gly-Asp-D-Phe-Lys）
b. Cyclo（RGDfV）: Cyclo（Arg-Gly-Asp-D-Phe-Val）
C. Arg * -Gly-Asp-D-Phe-Val-Glu * -Gly-Asp-D-Phe-Val (Glu * rings with Arg * amide bonds)
D. Arg-Gly-Asp-D-Phe-Val-Orn * -Gly-Asp-D-Phe-Val * (Orn * rings with Val * amide bonds)