Methylation modification (Me1, Me2, Me3)
Using high quality Fmoc-Lys(Me,Boc)-OH、 Fmoc-Lys(Me2)-OH、Fmoc-Lys(Me3)-OH.HCL、Fmoc-Arg(Me,Pbf)-OH 、Fmoc-Arg(me)2-OH.HCl(asymmetrical) 、Fmoc-Arg(me)2-OH.HCl(symmetrical) The polypeptide labeled with Lys methylation and Arg methylation was synthesized by Fmoc solid phase synthesis process. The product was purified by HPLC. The final product is provided with corresponding mass spectrograms, HPLC chromatograms for purity analysis, and COA.
Synthetic Case:
1. Pro-Arg-Thr-Pro-Pro-Arg(Me)-Pro-Ser-Gln-Gly-Lys-NH2
2. Biotin-Ile-Lys(Me)2-Gly-Glu-Phe-NH2
3. Pro-Arg(Me2, asymmetrical)-Ser-Lys-Asn-NH2